SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187917445e010bb21dd0b177de77e79e02c2946730fb6d91241bb893fdfd2f5f' 
  AND token = 'K8VDvRfjwyS7oAYWvNlJsznkxb5j/9mtY2+xx7PAiv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}