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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c343a701960b406e0cd59fe0116733ae497a53d22dbe8e0011d025911d96f25' 
  AND token = 'K0xbZvG3YczoqvO3XVFoAxTj4h6N8UnPuToSPfyFE5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}