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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4441a0fa46a3524b3973544f2ebbc04d7ee18d9f1ff13b90b9f7f6716e9a514d' 
  AND token = 'MDPIqmcMvRHx8iQOKff/GSWE4dqUQ7Q8IQ4twUJtXF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}