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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c878d8a019242f0f9a7f497b0589e197b6bccaf9f5e999ad502e4063cf906b81' 
  AND token = 'Yu5VI6y75iNNvCZtLi5cEa02oZtdvmyIYSEW4E4zf/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}