SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7214f7c56062d8e3136e952220d9fbb99a7f5feee551ec80307e712f5301b8fb' 
  AND token = 'GM0ecg8Mk6lxnVFIQlui3nL04u6+hsaOS2DUGJzEiX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}