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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6f90b37accd973da73778a999f91028c2f74be7ccf1a4a9e4446e4631d79f4' 
  AND token = 'hl9/9KC+atNWYQwPR9zQmlW601+XQfdBXMnRr8f5aVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}