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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd69f6450c46fb771c3ca8b7f9e485cdec20a0fbd2d2eef600e0c52298003c4af' 
  AND token = 'ufvKL9FOHia82ccoQ7Qq4JEviuQDrlqmkBLYh8ywGsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}