SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e770c979b7bb4d1a100d6ccd5f7a62e9f22d825ca99d7102f853a39b47df280' 
  AND token = 'Yt2P5oT944WnWNy3UU6+6vR5NlRHL5nYHtXmSb/5Es0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}