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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66a8a472e33a82129be968e0a9b45c5a62e3b2c42e661aa5027cde84b706f2d' 
  AND token = 'BpYN++TaHvCScsME5JHmdKLUIPC2lMG837ILFYQSqpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}