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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d9e8f1ffee33c0719dd93adc26f66ab56ed05671b2f8ed7f331ff6572a02650' 
  AND token = 'v7PxcOWJRdDUJOeskNF5W5jJq0Mb9XvFAcSrSZLNQWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}