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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453db44bcab37c028657f48f130042889bc492649508f437bbcd3be41a6bcc2a' 
  AND token = '+l08xDP6bKIQzMtiAx25GaP5fRNrOH1S0jVHNv4QnpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}