SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653ee753f33d72128a7fab050746f857c4bc7c3254949b2f2012b6d94017be2c' 
  AND token = 'ZwZvBlEyNKP4n0Zagvomq1ENFQsMC3WueU30jpLWmoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}