SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec15fccdb159cb5003f3dbf4d4db7c58e43afa462816a4631ead435c1ef6870e' 
  AND token = '+QuXtDOP+aYkO9D5MD1r+zUY8dfxt83sZwNHW+YdeJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}