SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e942fd51522c3e79964fd4fc64b0cf9a6556b93c00b8f1c6cafa46ff2e418f' 
  AND token = 'Q+Ez1vJkFZVf5Wmu44t3SQw+QYha6lhL8h10frrRgCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}