SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2019e0829a689ee644158b17529246760fcdbc6b9e0e7a16faa59049dd029ada' 
  AND token = '/ckthGZaqdenUTyt17lByfayv7w3nIjG4DXRogj+Nx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}