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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4d3b02f27d48e2c2004b58c1322ef8005aafab8ab1c1c97ee6730a268b44ef' 
  AND token = '0GEVAS96YAL3m8wT98ZJVyEQqH26dnSbnbD5B16E130=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}