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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bc0bf7100af5f8fe8fd0c2f790da028c4680cf6e84bee552e4eb882f3981c71' 
  AND token = 'zKQG6UmUgsTlTYwr1iOmS5NfvLn8iWjANlc+QAJjFsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}