SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9352abf1ad2240be455ef8da992a70c2dca7d65cb67126b6bc5547f1ee8c6ff3' 
  AND token = 'EuQTb/Lc3ixpOgqceqSyP2gk+d4WcjzbCswzIQ4QWm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}