SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd2b535c3ef58cf49f7d14d536835702f36a5bb04791d8995658f865dad8a7a' 
  AND token = 'yx01Kz++iej9No3+Pw2lT0yzQhAL5+V6CsogTFUIAKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}