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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bcd7e0995342549e7384c8d5344e7cb99692b90822ec085d1a2376e23dd0a77' 
  AND token = 'USOtHSOIr6K0eJVHvR8lyYGf9pZYMbxBbcdfGJDzroA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}