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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f919c41b76400a0fa768d2eab577d91b188ed777c5ef6c43aa63916ddcc9cc6' 
  AND token = 'J0QOAiLzVCjGuWq+DZoG2u7sIsbWJ4oJ6SV8AU36l4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}