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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7c60bd2068b496926b0c36057077a32e60067c5c7f62553dcc044a5f1dbefc' 
  AND token = 'Ac1PI8ahs3MOWAkXxzvZiYWzkRko9UW47L0EMOvR6gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}