SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c4c7e3fbb267832d1802fd6e3bc9f7dad0b4476609c933b50b69f6ed03f837' 
  AND token = 'PZ3mF+J04haLxpJEA50+KOtaIiJBt95gLRf+7/Bk4vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}