SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1607914c443fe3a370558230372e62a0ac0609e067ce234220ccdcfc1d6b466' 
  AND token = 'cfRrJ8Nxmv1/VdyDTr4FevWQTeElQ+IEnTSYN1kHg68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}