SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225ab76543e72a405276b39781884bd148a5ae4bb8f2cc6a481e8073f293ee54' 
  AND token = 'v4Qxanrcpe9RaqaV55gcn7pWCgKEhsqHR0AQB1/VMm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}