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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3efa7f09c52f4717d285df3876f6f227055d4e1aa5fa4be461e903da1dc322' 
  AND token = 'CKRL9VNEjIsYf50r7QAf+T/CY7n4prRe3T68k0MSRRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}