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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7a8a9077e1a0e36231eb68a25949352bd493b0c0c7be6c825253bfccbb3d82' 
  AND token = 'CUar1q7kf0hIA+H8UImNnwZ4afWrAo/g7EtEYTNidGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}