SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad546828fe4a72b8778b0a57dbb59e4db7498694670cae5f073fe9d87e40a538' 
  AND token = 'DlHf0ZAlelHdeo1g1He4h61R/DPcMqnJ1xICPuoZYSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}