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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6113eba90dd6b23642fb1e1d146a17d2318238cdde5640d8d5ae7da8a7ba84dc' 
  AND token = '8qe/p/BUe+GTfUaDqlpdVDSu+KnZGBQTPP4NuLwX9AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}