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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d5b4110d9fe77154dbb49fb3dcffa6b14d0ef7044115aa9617a55ce71a40d1' 
  AND token = 'ZmS1kRbijkvtg2+aP0ROeqXGW7cpzPhX99Px2oPhGV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}