SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '209fd6215021a5e09da09868ef227d0f698867f92beb9905e3a43f303bf9d5cb' 
  AND token = 'RXy9XIQxIROk9RDEXkFbU1UKpzRqQ3RwPzDR5z4EC/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}