SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc223c82fd157988cd6efa779c74bc910f4f1c47086dc9307fe5dd4678603e3' 
  AND token = 'zMPHxA9cTsE5zYwjX1/V6zF8gryG53ZwmlLxqEo117w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}