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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78165c139c091cde984e9e088d851ca9eac48a8bfa9298fdf86d1df66e995ba8' 
  AND token = 'WdqOO6tsp9kMbY1YZrj/Tv2BMut/ZXHJ5tq+rPjNW64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}