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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6cd4ab04135033d35c198e6a6ed95ecead2a8763e954d15aeeaa9dfdf6e6b48' 
  AND token = 'xrHCDdY6fDoO3vS2y/DITEYfKpfrzas+Ba0t+m5gPF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}