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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e963b2c8b11cf67a24f4a2aa953f897e9fc13640020b172cd329ec8679d2283' 
  AND token = 'sKn0g0FDbgXgIG8EHORf2vDWtJRBnvH0EBIMb8dRHl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}