SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795aac7682a8338e2fa40873b8f4019538e71db8e2acfcd98f3c8cd2586ddb15' 
  AND token = 'pwFyGvxmAvuvBrgKbFwDcpN43cn8Ct1ENTxuvtvFQ5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}