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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a426480b96b479415c8a1d3d0f8bc0e9515f51c7966a6ee6c5ab4961c558288f' 
  AND token = 'w+CzSDWexLGiRWQoBZ3a+ozYPxGbg81d++oRXv9KbNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}