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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d85217a9cd4f9fcb37c0b067d2c6a07c261306ff4a12fdcadc49188dd9a6d1' 
  AND token = '21oHwis/Eokk0d+CpqMUL1k59NxPtiVz6pHsCG65eD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}