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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '596aef74aab68f44b8404471dee33c4fd1e4e855cc0769508ed9daef8224e250' 
  AND token = '3DJdPFk7CrPHgYInt2DArF2n9eg5NUGO+UH/XDiUJac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}