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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591a2a35a669622ccd51240aceea18cc769a29528f81af0241e24ea4da7fdd7f' 
  AND token = 'QFv6go/grw+J8+LbF/g5FszNxF8zZ4XnM3W6OlD+zHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}