SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3418c1a96069e526e2be29916858194afc5209a76a1b00d6590a013bfb502697' 
  AND token = '9aofkVP15TC/oFoSCJN889VqRWOijtsD3RdO63mUicA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}