SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161fb7fb1bb419bcf76afc06d202fbe0f9f8aa56f714f1fad7b368cfb4982a62' 
  AND token = 'owFTG67WkqxoPvBZQ3S6YgtBRjrgMjQyD0UD0lYclpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}