SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26857a13eece0f1cad842d6f724005c0db29a7a8c15fb2e329e14b1fa24950c0' 
  AND token = 'AkB40r5VciPD0APN5fAq99U/5n3XxTeCt+noEyzR35A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}