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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd349a10f66a8731278aa8e26e1f27b05c57dfcc3b7f302a945482a20398b09b1' 
  AND token = '1065vCnHFxhdi1RIiyByY4yszg0vyeTcquVkmKHAKbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}