SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c50ff9e46ce3b0d75e2f9800823f79d0f854f199312ea33aa3039a673a8425' 
  AND token = 'e6ejNIMlMr5axD61GxAfXuGqc/ZPfwcDLk38uOST5s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}