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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df155f62b30de5ee10bb6675f1b995151d55b37faf15fe98b51292a1a63e7dc1' 
  AND token = 'FD8e5Uxgq6lA7XUATQpn1xgEsZ1kDjbrbhMBYz8tFr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}