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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dec23948986ca75f7ce2bbb8b9fc75987e664424565d2010576de706959a585' 
  AND token = 'kis8R+jKYVjvjaeFSjdKz5iL7R0LmasK1hQtlMbWAUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}