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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323c91e2e68e6e27816ee8a3347e8bb9cba1dd2e2e0fa16e048f066d3b977cff' 
  AND token = 'VcQwt6zpwy8OSjCVPqjSlVlwRYCu1OB8c2f5LIVI8iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}