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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a1b4418e35e41fb5f1954802d244653c616382fa9f461fb3d59f9429259df4' 
  AND token = 'y+J70lzMpKhuxV3OVSyjPIoyyX+uSj3sfkWqdZ1jrZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}