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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd23db73df13642e6ea4fe14e54bd5bfd683c80ff0f84eb8bdea23d721a7942' 
  AND token = 'yqTDq/ceYOpi9ofp4L0dY7I9g4zy0yXaVdVPUj630HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}